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The process has many advantages such as- Simple sterilization process Rapid process Effective in several products Safe and environment friendly Less time consuming Maintains product quality as such About Steam sterilization of Botanical/herbal powders Now we have understood much about sterilization and one of its types is steam sterilization. The second thing which is important to understand is why steam sterilization has an important role in making botanical powders. We know that the raw materials of botanical powder are roots, stems, and leaves of plants that grow in an open farm, then these plants are collected, cleaned, manually for further processing. The stems and leaves are cut down into small pieces and powdered with the help of a machine. In all of these steps, there is a high chance that microbes will contaminate the final manufactured herbal powder. Thus for killing all of the microbes we have to sterilize herbal powder. As we have mentioned that stem sterilization should be processed at a specific temperature that is 121 to 132 degrees Celsius, at specific pressure that is 1 atm (106 kPa) is recommended. The process runs for about 20-30 minutes. After that, we get our finish good. The steam sterilization process is best for botanical powder sterilization, as it is not involved with any other chemical reaction so maintains the product integrity. The process does not affect any bio-active component and composition of the botanical powder. Steam sterilizer (Autoclave) is the equipment used for the process. There are various types of autoclaves such as pressure cooker type, Vertical type, horizontal type, and common laboratory type in their several sizes and shapes. Specific can be used according to the quantity and type of product. Large industries commonly use big steam chambers for bulk production. 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